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在动物模型揭示神经，血液，创伤后应激障碍和行为相关因素的生物标志物
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Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD
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在动物模型揭示神经，血液，创伤后应激障碍和行为相关因素的生物标志物

15,675 Views

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08:29 min

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October 10, 2012

DOI:

10.3791/3361-v

DOI:
10.3791/3361-v

•

08:29 min
October 10, 2012

•

2 Views
, , , , , , , , ,
1Department of Psychiatry, Center for the Study of Traumatic Stress,Uniformed Services University of the Health Sciences, Bethesda, Maryland, 2Department of Gene and Protein Biomarkers,GenProMarkers, Inc.

Özet

Automatically generated

我们描述了一个大鼠模型的创伤后应激障碍（PTSD），揭示了神经内分泌功能的持久性的改变和长期延迟，夸大的恐惧反应，创伤后应激障碍患者的特征。的动物模型，和这里描述的方法，用于相关的生物标志物在脑核，这是机械的，但不能被测量的患者中，与外周血白细胞中的生物标志物，它可以是有用的。

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Jia, M., Meng, F., Smerin, S. E., Xing, G., Zhang, L., Su, D. M., Benedek, D., Ursano, R., Su, Y. A., Li, H. Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD. J. Vis. Exp. (68), e3361, doi:10.3791/3361 (2012).

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