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Isolating Nasal Olfactory Stem Cells from Rodents or Humans
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August 22, 2011
DOI:
1NICN,Aix Marseille University, 2LNPM,Aix Marseille University, 3ENT Department,Aix Marseille University, 4Gene expression Laboratory,The Salk Institute for Biological Studies, 5Laboratory of Speech and Language,Aix Marseille University, 6Centre d’Investigations Cliniques en Biothérapie,Aix Marseille University
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We describe here a method for biopsying olfactory mucosa from rat and human nasal cavities. These biopsies can be used for either identifying molecular anomalies in brain diseases or isolating multipotent adult stem cells that can be utilized for cell transplantation in animal models of brain trauma/disease.
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Girard, S. D., Devéze, A., Nivet, E., Gepner, B., Roman, F. S., Féron, F. Isolating Nasal Olfactory Stem Cells from Rodents or Humans. J. Vis. Exp. (54), e2762, doi:10.3791/2762 (2011).
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