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Methods to Assess Beta Cell Death Mediated by Cytotoxic T Lymphocytes
JoVE Journal
İmmünoloji ve Enfeksiyon
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JoVE Journal İmmünoloji ve Enfeksiyon
Methods to Assess Beta Cell Death Mediated by Cytotoxic T Lymphocytes

Methods to Assess Beta Cell Death Mediated by Cytotoxic T Lymphocytes

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12:12 min

June 16, 2011

DOI:

12:12 min
June 16, 2011

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Özet

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Cell-mediated lymphocytotoxicity (CML) assays can be used to test autoreactive responses and study mechanisms of cell death in vitro. However, using live-cell confocal microscopic imaging techniques with fluorescent dyes, the type and kinetics of cell death as well as the pathways utilized can be studied in greater detail.

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