Anti-retroviral therapy to treat HIV/AIDS is monitored in South Africa on a large scale. Flow cytometry is combined for haematology (CD45), immunology (CD4) and viral-load linked CD38 assay. Recorded at NHLS-SA laboratories, Johannesburg, these modern methods are cost-efficient with heightened local internal quality control, serving as role-models for resource-limited diagnostics.
Lawrie, D., Janossy, G., Roos, M., Glencross, D. K. Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model. J. Vis. Exp. (44), e2312, doi:10.3791/2312 (2010).