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Application of a NMDA Receptor Conductance in Rat Midbrain Dopaminergic Neurons Using the Dynamic Clamp Technique
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December 21, 2010
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In this video, we demonstrate how to apply a conductance into a dopaminergic neuron recorded in the whole cell configuration in rat brain slices. This technique is called the dynamic clamp.
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NMDA Receptor ConductanceRat Midbrain Dopaminergic NeuronsDynamic Clamp TechniqueNeuroscientistsBrain CommunicationElectrical ActivityPatch Clamp TechniquesGlass MicropipettesDirect Current InjectionIon ChannelsNeuronal MembraneRectangular PulsesKinetics Of Ion ChannelsChemical Changes In The CellReceptor ActivationElectrical StimulationPharmacological Stimulation
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Lobb, C. J., Paladini, C. A. Application of a NMDA Receptor Conductance in Rat Midbrain Dopaminergic Neurons Using the Dynamic Clamp Technique. J. Vis. Exp. (46), e2275, doi:10.3791/2275 (2010).
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