25.1:

Introduction to Lymphatic and Immune System

JoVE Core
Anatomy and Physiology
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JoVE Core Anatomy and Physiology
Introduction to Lymphatic and Immune System

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01:22 min

September 12, 2024

Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.

The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are born with, providing immediate but temporary protection against infections. On the other hand, adaptive immunity involves specific responses that our body learns and adapts over time, offering long-term and highly specialized defense against particular pathogens.

The lymphatic system is a pivotal component of the immune system. It facilitates the adaptive immune response and contributes to elements of innate immunity. This system encompasses four main components: lymph, lymphoid cells, lymphatic vessels, and lymphatic tissues and organs.

The lymph is a clear fluid acting as a transportation medium for lymphoid cells and proteins. Lymphoid cells are immune cells comprising lymphocytes, macrophages, and dendritic cells. Lymphocytes are white blood cells crucial for an adaptive immune response, while dendritic cells present antigens to activate these lymphocytes. Macrophages are primarily involved in the innate immune response, acting as phagocytes.

Lymphatic vessels form a comprehensive network for transporting lymph throughout the body. The lymphoid tissues and organs, including the spleen and thymus, offer lymphocyte maturation and activation sites.