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Cranial Nerves: Overview and Anatomy

JoVE Core
Anatomy and Physiology
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JoVE Core Anatomy and Physiology
Cranial Nerves: Overview and Anatomy

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01:19 min

March 28, 2024

The cranial nerves are an important part of the complex network of nerves in the human body. These nerves emerge directly from the brain and are responsible for transmitting essential information between the brain and various parts of the head and neck. There are 12 pairs of cranial nerves, systematically numbered using Roman numerals from I to XII, beginning from the anterior and moving to the posterior of the brain. Each cranial nerve is uniquely identified by names that reflect its function or the structure it innervates.

The cranial nerves are generally classified into three categories — sensory, motor, or mixed nerves. Whereas the sensory nerves detect information from the environment and the motor nerves control muscle movement, the mixed nerves have both sensory and motor functions.

Special Sensory Nerves: Nerves I (Olfactory), II (Optic), and VIII (Vestibulocochlear) fall under this category. They are responsible for the sensory modalities of olfaction, vision, hearing, and equilibrium, respectively. These nerves allow the human body to perceive and respond to external stimuli.

Motor Nerves: Nerves III (Oculomotor), IV (Trochlear), VI (Abducens), XI (Accessory), and XII (Hypoglossal) are classified as motor nerves. They primarily innervate muscles involved in eye, neck, and tongue movements, facilitating a range of actions from looking at different objects to swallowing and speech.

Mixed Nerves: Nerves V (Trigeminal), VII (Facial), IX (Glossopharyngeal), and X (Vagus) are known as mixed nerves because they carry both sensory and motor fibers. These nerves serve diverse functions, including facial sensation, mastication, taste, and salivation. They also control muscles in the oral cavity, pharynx, and some visceral organs. Their mixed nature allows them to participate in sensory perception and motor control of the head and neck regions and autonomic functions.

Parasympathetic Innervation

In addition to these functions, four cranial nerves—III (Oculomotor), VII (Facial), IX (Glossopharyngeal), and X (Vagus)—also play integral roles in the parasympathetic division of the autonomic nervous system (ANS). They are involved in involuntary functions such as regulating heart rate, digestion, and glandular secretions. For example, the Vagus nerve carries parasympathetic fibers to the heart, lungs, stomach, and digestive tract, and the Facial nerve carries parasympathetic fibers to stimulate salivary and lacrimal glands.