Experience-Dependent Remodeling of Juvenile Brain Olfactory Sensory Neuron Synaptic Connectivity in an Early-Life Critical Period

Nichalas Nelson; Vanessa Miller; Nicholas Baumann; Kendal Broadie

doi:10.3791/66629

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Olfactory Experience-Induced Synaptic Remodeling in Drosophila's Juvenile Brain

Olfactory Experience-Induced Synaptic Remodeling in Drosophila's Juvenile Brain

March 01, 2024

Author Spotlight: Exploring Glial Influence in Experience-Dependent Synaptic Pruning During Critical Periods

00:57 min

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379 Views

Inducing Ethyl Butyrate (EB) Experience-Dependent Synaptic Pruning of Or42a Receptor

01:21 min

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Drosophila Brain Dissection to Analyze Ethyl Butyrate (EB) Experience-Dependent Synaptic Pruning of Or42a Receptor

01:26 min

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Confocal Imaging and Synaptic Measurements to Analyze Experience-Dependent Critical Period Synaptic Glomeruli Pruning

03:34 min

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Nichalas Nelson*¹, Vanessa Miller*¹, Nicholas Baumann¹, Kendal Broadie^1,2,3,4,5

¹Department of Biological Sciences,Vanderbilt University and Medical Center, ²Department of Cell and Developmental Biology,Vanderbilt University and Medical Center, ³Department of Pharmacology,Vanderbilt University and Medical Center, ⁴Kennedy Center for Research on Human Development,Vanderbilt University and Medical Center, ⁵Vanderbilt Brain Institute,Vanderbilt University and Medical Center

Özet

We describe here methods for inducing and analyzing olfactory experience-dependent remodeling of antennal lobe synaptic glomeruli in the Drosophila juvenile brain.