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Fabricating Mouse Tendon Assembloids to Study Cellular Interactions in Disease
March 22, 2024
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Özet

Here, we present an assembloid model system to mimic tendon cellular crosstalk between the load-bearing tendon core tissue and an extrinsic compartment containing cell populations activated by disease and injury. As an important use case, we demonstrate how the system can be deployed to probe disease-relevant activation of extrinsic endothelial cells.