25.9:

Introduction to Innate and Adaptive Immunity

JoVE Core
Anatomy and Physiology
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JoVE Core Anatomy and Physiology
Introduction to Innate and Adaptive Immunity

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01:21 min

September 12, 2024

The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.

Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate, broad-spectrum response to various pathogens.

Adaptive immunity, on the other hand, is more specialized and evolves through exposure to different pathogens. This system activates lymphocytes, specifically B cells and T cells. B cells produce antibodies that neutralize specific pathogens, while T cells directly attack infected cells.

Both systems work together to provide a robust defense against a wide variety of pathogens.

Innate immunity offers an immediate response upon pathogen invasion, helping to contain the infection and activate the adaptive immune system. As a result, adaptive immunity produces a specific response to the particular pathogen, including the production of memory cells for effective response to future encounters with the same pathogen. Together, this potent duo ensures the body is prepared to face the same pathogen if exposed again.