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A Comprehensive Protocol for Delivering Intrathecal Injections in Neonatal Mice

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Iniezione intratecale di topo neonato per l'editing del genoma e la somministrazione di farmaci

JoVE Journal
Neurociência

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JoVE Journal Neurociência

Intrathecal Injection of Newborn Mouse for Genome Editing and Drug Delivery

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Iniezione intratecale di topo neonato per l'editing del genoma e la somministrazione di farmaci

A Comprehensive Protocol for Delivering Intrathecal Injections in Neonatal Mice

DOI:

10.3791/65761-v

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02:09 min

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March 08, 2024

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Xiaona Lu, Yong-hui Jiang^2,3

¹Department of Genetics,Yale University School of Medicine, ²Department of Neuroscience,Yale University School of Medicine, ³Department of Pediatrics,Yale University School of Medicine

Tags

Intrathecal Injection Newborn Mouse Genome Editing Drug Delivery Neurodevelopmental Disorder Gene Editing Central Nervous System Cerebrospinal Fluid Preclinical Studies Neurobehavioral Analysis IPSC ICV Injection Non-viral Non-nanoparticle

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