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マウスにおけるノルマザーミック Ex vivo 肝臓機械灌流
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JoVE Journal Engenharia
Normothermic Ex Vivo Liver Machine Perfusion in Mouse
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マウスにおけるノルマザーミック Ex vivo 肝臓機械灌流

1,809 Views

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13:14 min

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September 25, 2023

DOI:

10.3791/65363-v

DOI:
10.3791/65363-v

•

13:14 min
September 25, 2023

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30 Views
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1Experimental Transplantation Surgery, Department of General, Visceral and Vascular Surgery,Jena University Hospital, 2Institute of Pathology,Klinikum Chemnitz GmbH, 3Department of Pathology, Faculty of Veterinary Medicine,Menoufia University

Summary

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マウス肝臓用に正常体温 外生体外 肝灌流(NEVLP)システムが作成されました。このシステムはマイクロサージャリーの経験が必要ですが、再現性のある灌流結果を可能にします。マウスの肝臓を利用することで、分子経路の探索が容易になり、新規灌流液添加物が同定され、臓器修復に重点を置いた実験が可能になります。

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Cite this Article

Chen, H., Dirsch, O., Albadry, M., Ana, P. H., Dahmen, U. Normothermic Ex Vivo Liver Machine Perfusion in Mouse. J. Vis. Exp. (199), e65363, doi:10.3791/65363 (2023).

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