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The Serial Anesthesia Array for the High-Throughput Investigation of Volatile Agents Using Drosophila melanogaster
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Genética
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JoVE Journal Genética
The Serial Anesthesia Array for the High-Throughput Investigation of Volatile Agents Using Drosophila melanogaster

The Serial Anesthesia Array for the High-Throughput Investigation of Volatile Agents Using Drosophila melanogaster

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06:27 min

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February 24, 2023

DOI:

10.3791/65144-v

DOI:
10.3791/65144-v

•

06:27 min
February 24, 2023

•

6 Views
, , ,
1Department of Anesthesiology,University of Wisconsin-Madison, 2Department of Medical Genetics,University of Wisconsin-Madison

Summary

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The fruit fly (Drosophila melanogaster) is widely used for biological and toxicological research. To expand the utility of flies, we developed an instrument, the serial anesthesia array, that simultaneously exposes multiple fly samples to volatile general anesthetics (VGAs), making it possible to investigate the collateral effects (toxic and protective) of VGAs.

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Olufs, Z. P. G., Johnson-Schlitz, D., Wassarman, D. A., Perouansky, M. The Serial Anesthesia Array for the High-Throughput Investigation of Volatile Agents Using Drosophila melanogaster. J. Vis. Exp. (192), e65144, doi:10.3791/65144 (2023).

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