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利用可重构的迷宫系统提高啮齿动物空间导航测试的可重复性

JoVE Journal
Comportamento

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JoVE Journal Comportamento

Utilizing a Reconfigurable Maze System to Enhance the Reproducibility of Spatial Navigation Tests in Rodents

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利用可重构的迷宫系统提高啮齿动物空间导航测试的可重复性

DOI:

10.3791/64754-v

•

04:41 min

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December 02, 2022

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Fumiya Sawatani, Yuta Tamatsu, Kaoru Ide, Hirotsugu Azechi, Susumu Takahashi

¹Laboratory of Cognitive and Behavioral Neuroscience, Graduate School of Brain Science,Doshisha University

Capítulos

00:04Introduction
01:06Evaluation of Spacial Navigation of Rodents in the Reconfigurable Maze
01:47Behavioral Experiment, Performance, and Data Analysis
02:48Results: Maze Shapes in a Single Environment, Maze Expansion and Trajectories of a Rat, and the Performance of Maze Experiments
04:08Conclusion

Summary

Tadução automática

该协议描述了一个可重构的迷宫，这是一个用于测试啮齿动物空间导航和行为表型的独特系统。这种迷宫系统的适应性可以在单一的物理环境中执行各种实验。结构重排的便利性产生了可靠且可重复的实验结果。

Tags

Keywords: Reconfigurable Maze Spatial Navigation Rodents Behavioral Testing Maze Configuration Delayed Alternation Task Treadmill Pose Estimation Reproducibility

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