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Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
JoVE Journal
Neurociência
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JoVE Journal Neurociência
Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
DOI:

05:40 min

July 29, 2021

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Capítulos

  • 00:05Introduction
  • 00:36Dural Infuser
  • 02:12Dural Injections
  • 03:11Periorbital von Frey
  • 04:14Results: Dural Prolactin Stimulation in Mice as a Preclinical Headache Model
  • 05:07Conclusion

Summary

Tadução automática

The most notable symptom of migraine is severe head pain, and it is hypothesized that this is mediated by sensory neurons innervating the meninges. Here, we present a method to locally apply substances to the dura in a minimally invasive manner while using facial hypersensitivity as an output.

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