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Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
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Bioengenharia
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JoVE Journal Bioengenharia
Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

6,979 Views

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09:39 min

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February 07, 2021

DOI:

10.3791/62234-v

DOI:
10.3791/62234-v

•

09:39 min
February 07, 2021

•

12 Views
, , ,
1Department of Materials Science & Engineering,Stanford University, 2Department of Chemical Engineering,Stanford University, 3Department of Bioengineering,Stanford University, 4Department of Pediatrics – Endocrinology,Stanford University

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This protocol describes the synthesis and formulation of injectable, supramolecular polymer-nanoparticle (PNP) hydrogel biomaterials. Applications of these materials for drug delivery, biopharmaceutical stabilization, and cell encapsulation and delivery are demonstrated.

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InjectableSupramolecularPolymer-nanoparticleHydrogelsCell DeliveryDrug DeliveryNano-precipitationPEG-PLADynamic Light ScatteringHPMC-C12Rheological PropertiesDrug Release

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Meis, C. M., Grosskopf, A. K., Correa, S., Appel, E. A. Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications. J. Vis. Exp. (168), e62234, doi:10.3791/62234 (2021).

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