/
/
Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments
É necessária uma assinatura da JoVE para visualizar este conteúdo. Faça login ou comece sua avaliação gratuita.
Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments
4,271 Views
•
07:46 min
•
April 30, 2021
DOI:
Summary
Automatically generated
In the age of immunotherapy and single-cell genomic profiling, cancer biology requires novel in vitro and computational tools for investigating the tumor-immune interface in a proper spatiotemporal context. We describe protocols to exploit tumor-immune microfluidic co-cultures in 2D and 3D settings, compatible with dynamic, multiparametric monitoring of cellular functions.
Read Article
Cite this Article
De Ninno, A., Bertani, F. R., Gerardino, A., Schiavoni, G., Musella, M., Galassi, C., Mattei, F., Sistigu, A., Businaro, L. Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments. J. Vis. Exp. (170), e61895, doi:10.3791/61895 (2021).
Copy