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Optimization of Crystal Growth for Neutron Macromolecular Crystallography
JoVE Journal
Biologia
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JoVE Journal Biologia
Optimization of Crystal Growth for Neutron Macromolecular Crystallography

Optimization of Crystal Growth for Neutron Macromolecular Crystallography

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12:29 min

March 13, 2021

DOI:

12:29 min
March 13, 2021

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Summary

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Structural studies of biomacromolecules by crystallography require high-quality crystals. Here we demonstrate a protocol that can be used by OptiCrys (a fully automated instrument developed in our lab) and/or microdialysis buttons for growing large high-quality crystals based on knowledge of the crystallization phase diagram.

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