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Induction de lésion diffuse du cerveau axonal chez les rats basés sur l’accélération rotationnelle
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Induction de lésion diffuse du cerveau axonal chez les rats basés sur l’accélération rotationnelle
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06:14 min
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May 09, 2020
DOI:
1Division of Anesthesia and Critical Care, Soroka University Medical Center and the Faculty of Health Sciences,Ben-Gurion University of the Negev, 2Department of Neurosurgery, Soroka University Medical Center and the Faculty of Health Sciences,Ben-Gurion University of the Negev, 3Department of Anesthesiology,Yale University School of Medicine, 4Recanati School for Community Health Professions, Faculty of Health Sciences,Ben-Gurion University of the Negev, 5Department of microbiology and immunology, Faculty of Health Sciences,Ben-Gurion University of the Negev
Summary
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Ce protocole valide un modèle de rongeur fiable, facile à exécuter et reproductible de lésions axonales diffuses cérébrales (DAI) qui induit des dommages à la matière blanche généralisée sans fractures du crâne ou contusions.
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Cite this Article
Frank, D., Melamed, I., Gruenbaum, B. F., Grinshpun, J., Kuts, R., Shvartsur, R., Azab, A. N., Assadi, M. H., Vinokur, M., Boyko, M. Induction of Diffuse Axonal Brain Injury in Rats Based on Rotational Acceleration. J. Vis. Exp. (159), e61198, doi:10.3791/61198 (2020).
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