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小鼠完全转型脊髓损伤的诱导

JoVE Journal
Neurociência

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JoVE Journal Neurociência

Induction of Complete Transection-Type Spinal Cord Injury in Mice

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小鼠完全转型脊髓损伤的诱导

DOI:

10.3791/61131-v

•

06:51 min

•

May 06, 2020

•

Ronak Reshamwala^2,3, Tanja Eindorf³, Megha Shah³, Graham Smyth³, Todd Shelper³, James St. John*^1,2,3, Jenny Ekberg*^2,3

¹Griffith Institute for Drug Discovery,Griffith University, ²Menzies Health Institute Queensland,Griffith University, ³Clem Jones Centre for Neurobiology and Stem Cell Research,Griffith University

Capítulos

00:04Introduction
00:37Laminectomy
03:39Transection and Closure
04:54Results: Representative Transection Type Injury Results
06:13Conclusion

Summary

Tadução automática

该协议描述了如何创建精确的拉明切除术，在小鼠模型中诱导稳定的转节型脊髓损伤，为脊髓损伤研究提供最小的附带损伤。

Tags

Keywords: Spinal Cord Injury Transection Laminectomy Mouse Model Vertebrae Laminae Drill Dissection Forceps Surgical Procedure

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