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将类似蛋白的蛋白质定向组装到定义的超分子结构和体外货物封装中
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April 08, 2020
DOI:
1Center for Biological Systems Analysis,University of Freiburg, 2Faculty of Biology,University of Freiburg, 3Freiburg Institute for Advanced Studies (FRIAS),University of Freiburg, 4BIOSS Centre for Biological Signalling Studies,University of Freiburg, 5IMTEK Department of Microsystems Engineering,University of Freiburg, 6Cluster of Excellence livMatS at FIT – Freiburg Center for Interactive Materials and Bioinspired Technologies,University of Freiburg
Summary
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在有机溶剂和水性溶剂的界面上，定制的两栖乳素样蛋白质组装成复杂的超分子结构，如由环境参数触发的囊泡、纤维和焦质。所述装配协议产生具有可调特性的蛋白质膜型隔间 （PMBC），能够封装各种货物。
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Schreiber, A., Stühn, L. G., Geissinger, S. E., Huber, M. C., Schiller, S. M. Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro. J. Vis. Exp. (158), e60935, doi:10.3791/60935 (2020).
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