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Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy
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Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy
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April 17, 2020
DOI:
1Department of Surgery Campus Charité Mitte/Campus Virchow-Klinikum,Charité – Universitätsmedizin Berlin, 2Department of Visceral, Transplant and Thoracic Surgery,Medical University of Innsbruck, 3Charité Clinician Scientist Program,Berlin Institute of Health, 4Department of Psychiatry, Psychotherapy and Psychosomatics,RWTH Aachen University, 5Department of Cardiothoracic Surgery,University Medical Center Regensburg, 6Department of General, Visceral and Vascular Surgery,Charité – Universitätsmedizin Berlin
Summary
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We present a murine model of brain death induction in order to evaluate the influence of its pathophysiological effects on organs as well as on consecutive grafts in the context of solid organ transplantation.
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Ritschl, P. V., Hofhansel, L., Flörchinger, B., Oberhuber, R., Öllinger, R., Pratschke, J., Kotsch, K. Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy. J. Vis. Exp. (158), e60831, doi:10.3791/60831 (2020).
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