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Lipidomics and Transcriptomics in Neurological Diseases
JoVE Journal
Neurociência
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JoVE Journal Neurociência
Lipidomics and Transcriptomics in Neurological Diseases

Lipidomics and Transcriptomics in Neurological Diseases

3,173 Views

09:58 min

March 18, 2022

DOI:

09:58 min
March 18, 2022

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Summary

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This article presents a modular protocol for tissue lipidomics and transcriptomics, and plasma lipidomics in neurological disease mouse models targeting lipids underlying inflammation and neuronal activity, membrane lipids, downstream messengers, and mRNA-encoding enzymes/receptors underlying lipid function. Sampling, sample processing, extraction, and quantification procedures are outlined.

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