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体内新生小鼠皮层神经元的双光子成像

JoVE Journal
Neurociência

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JoVE Journal Neurociência

In Vivo Two-photon Imaging of Cortical Neurons in Neonatal Mice

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体内新生小鼠皮层神经元的双光子成像

11,738 Views

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06:24 min

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October 18, 2018

DOI:

10.3791/58340-v

DOI:

10.3791/58340-v

•

06:24 min

October 18, 2018

•

14 Views

Hidenobu Mizuno^1,2,3, Shingo Nakazawa^2,3, Takuji Iwasato^2,3

¹International Research Center for Medical Sciences (IRCMS),Kumamoto University, ²Division of Neurogenetics,National Institute of Genetics, ³Department of Genetics,SOKENDAI (The Graduate University for Advanced Studies)

Summary

我们提出了一种用于成像新生小鼠大脑皮层的活体双光子成像协议。该方法适用于分析皮层神经元的发育动态、控制神经元动力学的分子机制以及疾病模型神经元动力学的变化。

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