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1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology,Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy,Johns Hopkins University School of Medicine
Capítulos
- 00:04Título
- 00:49Tunable Spherical Poly(Lactic-Co-Glycolic Acid) (PLGA) Fabrication
- 03:30Tunable Polymeric Particle Fabrication
- 06:21Surface Protein Conjugation for Artificial Antigen Presenting Cell (aAPC) Creation
- 08:01Results: Representative Spherical and Ellipsoidal Particle Characterization
- 09:49Conclusion
Aquí, presentamos un protocolo de forma rápida y reproducible generar biológicamente inspirado, biodegradable articifical antígeno que presenta las células (aAPC) con tamaño ajustable, forma y presentación de proteína de la superficie de la célula de T expansión ex vivo o en vivo .
