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自组装多胺基多肽 Amphiphiles (PPAs) 及相关生物材料的简易合成协议
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JoVE Journal Química
Facile Protocol for the Synthesis of Self-assembling Polyamine-based Peptide Amphiphiles (PPAs) and Related Biomaterials
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自组装多胺基多肽 Amphiphiles (PPAs) 及相关生物材料的简易合成协议

DOI:
10.3791/57908-v

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08:55 min

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June 25, 2018

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, , ,
1Department of Pharmaceutical Sciences,University of Nebraska Medical Center

Capítulos

  • 00:04Título
  • 00:39General Protocol for Synthesis of PPAs
  • 04:36PPA Cleavage from Solid Support
  • 06:39Results: Confirming Successful Synthesis, Purification, and Self-assembly (PPAs)
  • 07:41Conclusion

Summary

Tadução automática

Tadução automática

多胺基肽 amphiphiles (PPAs) 的合成是一个重要的挑战, 由于存在多种胺氮, 这需要明智地使用保护组来掩盖这些反应功能。本文介绍了一种简便的制备这些新型自组装分子的方法。

Tags

Polyamine-based Peptide AmphiphilesPPAsBiomaterialsProtecting GroupsHybrid Peptide Amphiphiles2-Chlorotrityl Chloride ResinPolyamineDDEBoc AnhydrideFmoc Protected Amino AcidHBTUDIPEA

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