This content is Free Access.
1Department of Neurobiology, F. M. Kirby Neurobiology Center,Boston Children’s Hospital, Harvard Medical School, 2Proteomic Mass Spectrometry,Wellcome Trust Sanger Institute, Wellcome Genome Campus, 3Centre for Molecular Informatics, Department of Chemistry,University of Cambridge, 4Functional Proteomics Group, Chester Beatty Laboratories,Institute of Cancer Research
Capítulos
- 00:05Título
- 00:51Mapping of Peptides using PoGoGUI
- 02:36Visualizing in the Integrative Genomics Viewer
- 03:57Mapping Peptides Identified Through a Custom Variant Database to a Reference Genome
- 04:44Mapping Peptides from Multiple Files Using PoGoGUI
- 05:48Generating a Track Hub from Mapped Peptides and Visualizing a Track Hub in the UCSC Genome Browser
- 06:50Results: Post-translational Modification and Varient Enabled Mapping of Peptides to Genomes
- 08:21Conclusion
Her præsenterer vi værktøjet proteogenomic PoGo og protokoller for hurtig, kvantitative, posttranslationel modifikation og variant aktiveret kortlægning af peptider identificeret gennem massespektrometri på reference genomer. Dette værktøj er nyttig til at integrere og visualisere proteogenomic og personlige proteom undersøgelser grænseflade med ortogonale genomforskning data.
