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Oprettelse af musemodeller for Zika Virus-induceret neurologiske lidelser ved hjælp af intracerebralt injektion strategier: embryonale, Neonatal og voksne
JoVE Journal
Neurociência
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JoVE Journal Neurociência
Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult

Oprettelse af musemodeller for Zika Virus-induceret neurologiske lidelser ved hjælp af intracerebralt injektion strategier: embryonale, Neonatal og voksne

DOI:
10.3791/56486-v

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09:39 min

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April 26, 2018

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, , , ,
1Biomedical and Health Sciences Institute,University of Georgia, 2Center for Craniofacial Molecular Biology,University of Southern California, 3Department of Infectious Diseases, College of Veterinary Medicine,University of Georgia

Capítulos

  • 00:04Título
  • 01:07Intracerebral Zika Virus Inoculation in Embryos
  • 04:02Intracerebral Zika Virus Inoculation in Neonates
  • 06:06Intracerebral Zika Virus Inoculation in Adult Mice
  • 07:53Results: Representative Histology in ZIKV-inoculated Embryos, Neonates, and Adult Mice
  • 08:57Conclusion

Summary

Tadução automática

Tadução automática

Her beskriver vi en metode til fastlæggelse af en model af Zika virus-induceret microcephalus i musen. Denne protokol omfatter metoder til embryonale, neonatal og voksne-fase intracerebralt podning af virussen Zika.

Tags

Zika VirusMouse ModelIntracerebral InjectionEmbryonicNeonatalAdultIn VivoBrain InfectionMicrocephalyNeuro-developmental DisordersFlavivirusDengue VirusSurgical ProcedureAnesthesiaEmbryo ExposureVirus Inoculation

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