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诱导麻痹及视觉系统损伤小鼠 T 细胞特异的视神经脊髓炎抗原水通道蛋白-4
JoVE Journal
Imunologia e Infecção
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JoVE Journal Imunologia e Infecção
Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
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诱导麻痹及视觉系统损伤小鼠 T 细胞特异的视神经脊髓炎抗原水通道蛋白-4

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09:29 min

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August 21, 2017

DOI:

10.3791/56185-v

DOI:
10.3791/56185-v

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09:29 min
August 21, 2017

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1 Views
, , , , , , ,
1Department of Neurology,University of California, 2Program in Immunology,University of California, 3Department of Neurology and Neurological Sciences,Stanford University, 4Department of Pathology,Stanford University

Tags

Neuromyelitis OpticaAquaporin-4T CellsAdoptive TransferCentral Nervous System Autoimmune DiseaseOptical Coherence TomographyRetinal InjuryComplete Freund’s AdjuvantEmulsionSubcutaneous Injection

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Sagan, S. A., Cruz-Herranz, A., Spencer, C. M., Ho, P. P., Steinman, L., Green, A. J., Sobel, R. A., Zamvil, S. S. Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4. J. Vis. Exp. (126), e56185, doi:10.3791/56185 (2017).

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