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A Pressure Injection System for Investigating the Neuropharmacology of Information Processing in Awake Behaving Macaque Monkey Cortex
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A Pressure Injection System for Investigating the Neuropharmacology of Information Processing in Awake Behaving Macaque Monkey Cortex

A Pressure Injection System for Investigating the Neuropharmacology of Information Processing in Awake Behaving Macaque Monkey Cortex

8,134 Views

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09:46 min

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March 14, 2016

DOI:

10.3791/53724-v

DOI:
10.3791/53724-v

•

09:46 min
March 14, 2016

•

1 Views
, ,
1Cognitive Neuroscience Laboratory,German Primate Center, 2Faculty of Biology and Psychology,Goettingen University

Summary

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Here, we show the pressure injection of neuropharmacological substances during single-cell recording in an awake, behaving macaque monkey. This procedure allows pharmacological manipulation in the direct vicinity of a cortical recording site.

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Pressure Injection SystemNeuropharmacologyInformation ProcessingAwake Behaving Macaque Monkey CortexFeedforward Cortical Information ProcessingNeurotransmitter SystemsSingle Cell RecordingsPharmacological InjectionsQuartz Glass MicropipetteSterile TubeSuperglueMicroelectrodesSterile Silicon Oil

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Veith, V. K., Quigley, C., Treue, S. A Pressure Injection System for Investigating the Neuropharmacology of Information Processing in Awake Behaving Macaque Monkey Cortex. J. Vis. Exp. (109), e53724, doi:10.3791/53724 (2016).

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