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3D modellering van de laterale ventrikels en histologische karakterisering van periventriculaire Tissue bij de mens en muis
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Neurociência
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JoVE Journal Neurociência
3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse
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3D modellering van de laterale ventrikels en histologische karakterisering van periventriculaire Tissue bij de mens en muis

DOI:
10.3791/52328-v

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15:26 min

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May 19, 2015

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, , , , , , ,
1Department of Physiology and Neurobiology,University of Connecticut, 2Department of Anatomic Pathology and Laboratory Medicine,University of Connecticut Health Center

Capítulos

  • 00:05Título
  • 02:10Analysis of Periventricular Cellular Integrity and 3D Modeling of the Mouse Lateral Ventricle
  • 06:24Modeling the Human Lateral Ventricle Using MRI Data
  • 09:06Longitudinal Representation of Lateral Ventricles from MRI Data
  • 10:40Human Periventricular Tissue Preparation and Analysis
  • 12:59Results: 3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans
  • 14:41Conclusion

Summary

Tadução automática

Tadução automática

Using MRI scans (human), 3D imaging software, and immunohistological analysis, we document changes to the brain’s lateral ventricles. Longitudinal 3D mapping of lateral ventricle volume changes and characterization of periventricular cellular changes that occur in the human brain due to aging or disease are then modeled in mice.

Tags

Keywords: 3D ModelingLateral VentriclesEpendymal CellsVentriculomegalyCerebral Spinal FluidBrain AgingImmunohistochemistryMRIMouse Models

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