É necessária uma assinatura da JoVE para visualizar este conteúdo. Faça login ou comece sua avaliação gratuita.
Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
17,824 Views
•
13:37 min
•
June 20, 2014
DOI:
Summary
Automatically generated
Peptide tertiary amides (PTAs) are a superfamily of peptidomimetics that include but are not limited to peptides, peptoids and N-methylated peptides. Here we describe a synthetic method which combines both split-and-pool and sub-monomer strategies to synthesize a one-bead one-compound library of PTAs.
Read Article
Cite this Article
Gao, Y., Kodadek, T. Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library. J. Vis. Exp. (88), e51299, doi:10.3791/51299 (2014).
Copy