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In-vivo-Imaging von Optic Nerve Fiber Integrität von Contrast-Enhanced MRI in Mäuse
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Neurociência
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JoVE Journal Neurociência
In vivo Imaging of Optic Nerve Fiber Integrity by Contrast-Enhanced MRI in Mice
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In-vivo-Imaging von Optic Nerve Fiber Integrität von Contrast-Enhanced MRI in Mäuse

13,194 Views

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11:38 min

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July 22, 2014

DOI:

10.3791/51274-v

DOI:
10.3791/51274-v

•

11:38 min
July 22, 2014

•

2 Views
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1Hans Berger Department of Neurology,Jena University Hospital, 2Immunology, Leibniz Institute for Age Research,Fritz Lipmann Institute, Jena, 3Institute of Diagnostic and Interventional Radiology, Medical Physics Group,Jena University Hospital

Summary

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Dieses Video zeigt ein Verfahren, mit einem klinischen 3 T Scanner, für kontrastverstärkte MR-Bildgebung des naiven Maus visuelle Projektion und für sich wiederholende und Längs in-vivo-Studien der Sehnerv-Degeneration mit akuter Sehnerven Quetschverletzung und chronische Degeneration des Sehnervs an assoziierten Knock-out-Mäusen (p50 KO).

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Cite this Article

Fischer, S., Engelmann, C., Herrmann, K., Reichenbach, J. R., Witte, O. W., Weih, F., Kretz, A., Haenold, R. In vivo Imaging of Optic Nerve Fiber Integrity by Contrast-Enhanced MRI in Mice. J. Vis. Exp. (89), e51274, doi:10.3791/51274 (2014).

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