Journal
/
Neurociência
/
In vivo Imaging of Optic Nerve Fiber Integrity by Contrast-Enhanced MRI in Mice
JoVE Journal
Neurociência
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Neurociência
In vivo Imaging of Optic Nerve Fiber Integrity by Contrast-Enhanced MRI in Mice

In vivo Imaging of Optic Nerve Fiber Integrity by Contrast-Enhanced MRI in Mice

13,198 Views

•

11:38 min

•

July 22, 2014

DOI:

10.3791/51274-v

DOI:
10.3791/51274-v

•

11:38 min
July 22, 2014

•

2 Views
, , , , , , ,
1Hans Berger Department of Neurology,Jena University Hospital, 2Immunology, Leibniz Institute for Age Research,Fritz Lipmann Institute, Jena, 3Institute of Diagnostic and Interventional Radiology, Medical Physics Group,Jena University Hospital

Summary

Automatically generated

This video illustrates a method, using a clinical 3 T scanner, for contrast-enhanced MR imaging of the naïve mouse visual projection and for repetitive and longitudinal in vivo studies of optic nerve degeneration associated with acute optic nerve crush injury and chronic optic nerve degeneration in knock-out mice (p50KO).

Explore More Videos

In Vivo ImagingOptic NerveMRIContrast EnhancementMEMRIRodent Visual SystemRetinal Ganglion CellsAxonal DegenerationAxonal RegenerationSynaptic PlasticityMnCl2NF-κB P50KO Mice

Read Article

Cite this Article

Fischer, S., Engelmann, C., Herrmann, K., Reichenbach, J. R., Witte, O. W., Weih, F., Kretz, A., Haenold, R. In vivo Imaging of Optic Nerve Fiber Integrity by Contrast-Enhanced MRI in Mice. J. Vis. Exp. (89), e51274, doi:10.3791/51274 (2014).

Download .ris file

Copy

Share Video

.

Copy