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人类前列腺癌转移的原位小鼠模型
JoVE Journal
Medicina
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JoVE Journal Medicina
An Orthotopic Murine Model of Human Prostate Cancer Metastasis
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人类前列腺癌转移的原位小鼠模型

DOI:
10.3791/50873-v

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06:48 min

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September 18, 2013

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, ,
1Department of Medicine,Northwestern University, 2Robert H. Lurie Cancer Center,Northwestern University, 3Center for Molecular Innovation and Drug Discovery,Northwestern University

Capítulos

  • 00:05Título
  • 01:32Orthotopic Implantation of Human Prostate Cancer Cells
  • 02:35Necropsy Procedures
  • 03:39Results: Identification and Quantification of Metastases in a Murine Human Pancreatic Cancer Model
  • 06:27Conclusion

Summary

Tadução automática

Tadução automática

人前列腺癌原位此模型允许对肿瘤大小进行量化，循环肿瘤细胞，并形成明显的转移到肺。由于细胞必须逃脱的主要器官，进入血流，并植入到辅助站点，这种模式有效地概括了情景在人。

Tags

Prostate CancerOrthotopic ModelMetastasisPreclinical ModelCirculating Tumor CellsLung MetastasisTherapeutic Response

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