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隔离和幼稚的CD4 T细胞的Th17细胞分化
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Imunologia e Infecção
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JoVE Journal Imunologia e Infecção
Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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隔离和幼稚的CD4 T细胞的Th17细胞分化

33,922 Views

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12:59 min

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September 26, 2013

DOI:

10.3791/50765-v

DOI:
10.3791/50765-v

•

12:59 min
September 26, 2013

•

10 Views
, , , ,
1Department of Microbiology and Cell Science,The University of Florida

Summary

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与效应器功能从其它的T细胞亚群的不同的，Th17细胞已被集中牵连的炎性自身免疫性疾病。这种体外 Th17细胞分化协议提供了一种方法来确定初始CD4 + T淋巴细胞是否能够分化成Th17细胞，并进一步研究其在自身免疫和宿主反应的作用。

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Cite this Article

Bedoya, S. K., Wilson, T. D., Collins, E. L., Lau, K., Larkin III, J. Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes. J. Vis. Exp. (79), e50765, doi:10.3791/50765 (2013).

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