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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
JoVE Revista
Inmunología y contagio
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JoVE Revista Inmunología y contagio
Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

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12:59 min

September 26, 2013

DOI:

12:59 min
September 26, 2013

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Summary

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With effector functions distinct from other T cell subsets, Th17 cells have been centrally implicated in inflammatory autoimmunity. This in vitro Th17 differentiation protocol provides a means to determine whether naïve CD4+ T lymphocytes can differentiate into Th17 cells, and to further examine their role in autoimmunity and host response.

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