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Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
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Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
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August 09, 2012
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Surgical stages of bladder augmentation are described using 3-D scaffolds in murine and rat models. To test the efficacy of biomaterial configurations for use in bladder augmentation, techniques for both awake and anesthetized cystometry are presented.
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BiomaterialsBladder AugmentationCystometric AnalysesRodent ModelsRenal FunctionContinence Of UrineUrinary BladderLow PressureContractionCongenital AnomaliesAcquired Urological AnomaliesPosterior Urethral ValvesBenign Prostatic HyperplasiaNeurogenic BladderSpina BifidaSpinal Cord InjuryImpaired ComplianceReduced CapacityUrinary Tract ObstructionUrinary IncontinenceKidney DamageSurgical ImplantationGastrointestinal SegmentsOrgan Capacity ExpansionIntravesical Pressures ReductionComplicationsChronic Urinary Tract InfectionMetabolic PerturbationUrinary Stone FormationSecondary MalignancyBiomaterial Configurations
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Tu, D. D., Seth, A., Gil, E. S., Kaplan, D. L., Mauney, J. R., Estrada Jr., C. R. Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models. J. Vis. Exp. (66), e3981, doi:10.3791/3981 (2012).
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