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Groei Mycobacterium tuberculosis Biofilms
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09:03 min
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February 15, 2012
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Mycobacterium tuberculosis vormt drug tolerant biofilms wanneer gekweekt in bepaalde omstandigheden. Hier beschrijven werkwijzen voor het kweken M. tuberculose biofilms en het bepalen van de frequentie van de drug tolerante persisters. Deze protocollen zullen nuttig zijn voor verdere studies naar de mechanismen van tolerantie in M. tuberculose.
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Mycobacterium TuberculosisGrowthBiofilmsStress ToleranceAntibioticsSurvivalMolecular MechanismsPathogenSelf-assemblingSurface AttachedMatrix Encapsulated StructuresBiofilm GrowthCommunitiesGenetic ComponentsSurface AttachmentIntercellular CommunicationsExtracellular Polymeric Substances (EPS)Environmental Stress TolerancePhysiological AdaptationBacilliComplex ArchitectureAnti-tuberculosis DrugsIsoniazidRifampicin
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Cite this Article
Kulka, K., Hatfull, G., Ojha, A. K. Growth of Mycobacterium tuberculosis Biofilms. J. Vis. Exp. (60), e3820, doi:10.3791/3820 (2012).
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