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의 이미징 HIV-1 봉투 유발 Virological 시냅스와 합성 지질 Bilayers에 신호
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March 08, 2012
DOI:
1Department of Pathology,New York University Langone School of Medicine, 2Program in Molecular Pathogenesis,Marty and Helen Kimmel Center for Biology and Medicine and Skirball Institute for Biomolecular Medicine, 3Laboratory of Molecular Immunogenetics, National Institute of Arthritis and Musculoskeletal and Skin Diseases,National Institutes of Health, 4Veteran Affairs New York Harbor Healthcare System
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HIV-1EnvelopeVirological SynapseSignalingSynthetic Lipid BilayersCell To Cell TransmissionCD4+ T CellsF-actinGp120Chemokine Receptor (CKR)CCR5CXCR4LFA-1ICAM FamilyVirus-infected Donor CellsTarget CellsHIV-1 VirionsIntracellular Signaling EventsTCR SignalosomeLckCD3ζZAP70LATSLP-76ItkPLCγSupramolecular Arrangement
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Prins, K. C., Vasiliver-Shamis, G., Cammer, M., Depoil, D., Dustin, M. L., Hioe, C. E. Imaging of HIV-1 Envelope-induced Virological Synapse and Signaling on Synthetic Lipid Bilayers. J. Vis. Exp. (61), e3757, doi:10.3791/3757 (2012).
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