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JoVE Journal Neuroscience
Large-scale Recording of Neurons by Movable Silicon Probes in Behaving Rodents
 

Large-scale Recording of Neurons by Movable Silicon Probes in Behaving Rodents

Article DOI: 10.3791/3568-v • 17:38 min • March 4th, 2012
March 4th, 2012 •
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1Center for Molecular and Behavioral Neuroscience, University of New Jersey, 2Center for Interdisciplinary Research in Biology, Collège de France, 3Janelia Farm Research Campus, Howards Hughes Medical Institute, 4Deptartment of Psychology, University of Wisconsin at Milwaukee

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We describe methods for large-scale recording of multiple single units and local field potential in behaving rodents with silicon probes. Drive fabrication, probe attachment to the drive and probe implantation processes are illustrated in sufficient details for easy replication.

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Neuroscience Large-scale Recording Movable Silicon Probes Behaving Rodents Neural Assemblies Input-output Relationships Spatial Selectivity Temporal Resolution Mechanistic Analysis Neural Ensembles Multiple-site Recording Silicon-based Devices Micro-machined Silicon Probes Custom-made Accessory Components Preamplifiers Printed Circuit Boards Flexible Cables Bonding Service Implantation 4-shank Probe 32-site Probe Polyimide Cable Movable Microdrive
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