/
/
Fluido laterale Percussioni: Modello delle lesioni cerebrali traumatiche nei topi
This content is Free Access.
Fluido laterale Percussioni: Modello delle lesioni cerebrali traumatiche nei topi
39,812 Views
•
11:04 min
•
August 22, 2011
DOI:
1Department of Neuroscience and Cell Biology,University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, 2Spinal Cord and Brain Injury Research Center, 3Department of Anatomy and Neurobiology, Department of Physical Medicine and Rehabilitation,University of Kentucky Chandler Medical Center
Summary
Automatically generated
Laterale fluido percussioni (LFP), un modello stabilito di lesioni cerebrali traumatiche nei topi, è dimostrato. LFP soddisfa tre criteri principali per i modelli animali: rilevanza validità, l'affidabilità e la clinica. La procedura, che consiste di craniotomia chirurgica, la fissazione del mozzo seguita da induzione di lesioni, con conseguente lesioni focali e diffuse, è descritto.
Explore More Videos
Lateral Fluid PercussionTraumatic Brain InjuryTBI ResearchHead InjuriesMorbidityMortalityPrimary InjurySecondary ConsequencesRegenerative ProcessesContusionSkull FractureShearingStretchingDisplacement Of BrainHematomasLacerationsVascular ResponseWhite Matter DamageDiffuse Axonal InjuryEdemaIncreased Intracranial PressureMicroscopic AlterationsExcitotoxic NeurotransmittersImmune MediatorsOxygen RadicalsLong-term Neurological DisabilitiesAnimal Models Of TBICellular EventsMolecular Events
Read Article
Cite this Article
Alder, J., Fujioka, W., Lifshitz, J., Crockett, D. P., Thakker-Varia, S. Lateral Fluid Percussion: Model of Traumatic Brain Injury in Mice. J. Vis. Exp. (54), e3063, doi:10.3791/3063 (2011).
Copy