A murine model for myocardial ischemia and ischemic preconditioning is an important tool study cardioprotective mechanisms in vivo. Here, we report an easy applicable in situ model for cardiac IP using a hanging-weight system for coronary artery occlusion.
Eckle, T., Koeppen, M., Eltzschig, H. Use of a Hanging Weight System for Coronary Artery Occlusion in Mice. J. Vis. Exp. (50), e2526, doi:10.3791/2526 (2011).