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Preparación de la aguda rodajas de hipocampo de ratas y ratones transgénicos para el estudio de las alteraciones sinápticas durante el envejecimiento y la patología amiloide
JoVE Journal
Neurociência
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JoVE Journal Neurociência
Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Preparación de la aguda rodajas de hipocampo de ratas y ratones transgénicos para el estudio de las alteraciones sinápticas durante el envejecimiento y la patología amiloide

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14:57 min

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March 23, 2011

DOI:

10.3791/2330-v

DOI:
10.3791/2330-v

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14:57 min
March 23, 2011

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1Graduate Center for Gerontology,University of Kentucky College of Public Health, 2Department of Molecular and Biomedical Pharmacology,University of Kentucky College of Medicine, 3Sanders-Brown Center on Aging,University of Kentucky College of Medicine

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Acute Hippocampal SlicesRatsTransgenic MiceSynaptic AlterationsAgingAmyloid PathologySynaptic FunctionPlasticityElectrophysiological TechniquesCognitive ImpairmentsSynaptic Plasticity MechanismsLong-term PotentiationLong-term DepressionNootropic CompoundsBrain AgingAlzheimer’s Disease (AD)Aged RatsAD Model Mice

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Mathis, D. M., Furman, J. L., Norris, C. M. Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology. J. Vis. Exp. (49), e2330, doi:10.3791/2330 (2011).

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