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突触改变老化过程中淀粉样蛋白病理研究从大鼠和转基因小鼠海马急性片的制备
JoVE Journal
Neurociência
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JoVE Journal Neurociência
Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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突触改变老化过程中淀粉样蛋白病理研究从大鼠和转基因小鼠海马急性片的制备

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14:57 min

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March 23, 2011

DOI:

10.3791/2330-v

DOI:
10.3791/2330-v

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14:57 min
March 23, 2011

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2 Views
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1Graduate Center for Gerontology,University of Kentucky College of Public Health, 2Department of Molecular and Biomedical Pharmacology,University of Kentucky College of Medicine, 3Sanders-Brown Center on Aging,University of Kentucky College of Medicine

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Acute Hippocampal SlicesRatsTransgenic MiceSynaptic AlterationsAgingAmyloid PathologySynaptic FunctionPlasticityElectrophysiological TechniquesCognitive ImpairmentsSynaptic Plasticity MechanismsLong-term PotentiationLong-term DepressionNootropic CompoundsBrain AgingAlzheimer’s Disease (AD)Aged RatsAD Model Mice

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Mathis, D. M., Furman, J. L., Norris, C. M. Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology. J. Vis. Exp. (49), e2330, doi:10.3791/2330 (2011).

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