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浆液性卵巢癌原位模型在免疫小鼠，为在体内肿瘤显像和肿瘤免疫反应的监测

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Imunologia e Infecção

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JoVE Journal Imunologia e Infecção

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses

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浆液性卵巢癌原位模型在免疫小鼠，为在体内肿瘤显像和肿瘤免疫反应的监测

DOI:

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10:35 min

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November 28, 2010

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Selene Nunez-Cruz, Denise C. Connolly, Nathalie Scholler

¹Penn Ovarian Cancer Research Center, Center for Research on Reproduction and Womans Health, Department of Obstetrics and Gynecology,University of Pennsylvania-School of Medicine, ²Women’s Cancer Program,Fox Chase Cancer Center

Capítulos

00:05Título
01:08Introduction
01:45The Syngeneic Model
03:43Cell Culture
04:34Pre-Surgery
05:48Surgery
07:27In vivo Imaging
09:20Representative in vivo and ex vivo Images
10:06Conclusion

Summary

Tadução automática

研究<em>在体内</em>肿瘤的生长和肿瘤微环境中，我们用在免疫动物的同源和原位卵巢癌的小鼠模型。我们转Katushka荧光蛋白（MOV1一只老鼠的肿瘤细胞株（MOV1）<sup> KAT</sup>），我们在这里展示其在卵巢原位移植和<em>在体内</em>成像。

Tags

Orthotopic Model Serous Ovarian Cancer Immunocompetent Mice In Vivo Tumor Imaging Tumor Immune Responses Tg-MISIIR-TAg Transgenic Mouse Model SV40 Transforming Region Mullerian Inhibitory Substance Type II Receptor (MISIIR) Gene Promoter Syngeneic Allograft Recipients Preclinical Studies Tumor Microenvironment

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