É necessária uma assinatura da JoVE para visualizar este conteúdo. Faça login ou comece sua avaliação gratuita.
カポジ肉腫関連ヘルペスウイルス（KSHV）によって誘発される調節不全遺伝子を特定
12,422 Views
•
07:02 min
•
September 14, 2010
DOI:
Summary
Automatically generated
宿主細胞因子がカポジ肉腫（KS）の確立と維持において重要な役割を果たす。我々は、KSHV感染DMVEC細胞に、とKS腫瘍組織に改変宿主細胞因子を特定する方法の概要を示します。ウイルスによって変更さ細胞の遺伝子は、新規な治療のための潜在的なターゲット（複数可）として機能します。
Explore More Videos
Kaposi’s Sarcoma-associated HerpesvirusDysregulated GenesKSHVHIV/AIDSMalignancySouthern AfricaAngioproliferative TumorVascular Endothelial CellsB Cell Lymphoproliferative DiseasesPleural Effusion LymphomasMulticentric Castleman’s DiseaseLytic ReplicationOncogenesisTumor ProgressionHost-factor DeterminantsPrognostic MarkersMetastasisTherapeuticsDermal Microvascular Endothelial Cells (DMVEC)Microarray AnalysisProtein ExpressionImmunoblotDual Labeled ImmunofluorescenceTranscriptional ExpressionQuantitative Real-time Polymerase Chain Reaction (qRT-PCR)
Read Article
Cite this Article
Alcendor, D., Knobel, S. Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV). J. Vis. Exp. (43), e2078, doi:10.3791/2078 (2010).
Copy