Maria Summa Drug Discovery and Development Istituto Italiano di Tecnologia Biography Publications Institution JoVE Articles Maria Summa has not added a biography. If you are Maria Summa and would like to personalize this page please email our Author Liaison for assistance. Publications First New World Primate Papillomavirus Identification in the Atlantic Forest, Brazil: Alouatta Guariba Papillomavirus 1 Genome Announcements. Aug, 2016 | Pubmed ID: 27540053 Endogenous N-acyl Taurines Regulate Skin Wound Healing Proceedings of the National Academy of Sciences of the United States of America. Jul, 2016 | Pubmed ID: 27412859 Second-Generation Non-Covalent NAAA Inhibitors Are Protective in a Model of Multiple Sclerosis Angewandte Chemie (International Ed. in English). Sep, 2016 | Pubmed ID: 27404798 Relationship Between Vitamin D and Body Fat Distribution Evaluated by DXA in Postmenopausal Women Nutrition (Burbank, Los Angeles County, Calif.). Jun, 2016 | Pubmed ID: 26856648 Hit Optimization of 5-Substituted-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamides: Potent Glycogen Synthase Kinase-3 (GSK-3) Inhibitors with in Vivo Activity in Model of Mood Disorders Journal of Medicinal Chemistry. Nov, 2015 | Pubmed ID: 26486317 Controlled Antiseptic/eosin Release from Chitosan-based Hydrogel Modified Fibrous Substrates Carbohydrate Polymers. Oct, 2015 | Pubmed ID: 26256189 3,4-Dihydro-1,3,5-triazin-2(1H)-ones As the First Dual BACE-1/GSK-3β Fragment Hits Against Alzheimer's Disease ACS Chemical Neuroscience. Oct, 2015 | Pubmed ID: 26171616 Activity-Based Probe for N-Acylethanolamine Acid Amidase ACS Chemical Biology. Sep, 2015 | Pubmed ID: 26102511 Multitarget Fatty Acid Amide Hydrolase/cyclooxygenase Blockade Suppresses Intestinal Inflammation and Protects Against Nonsteroidal Anti-inflammatory Drug-dependent Gastrointestinal Damage FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2015 | Pubmed ID: 25757568 Multitarget Drug Discovery for Alzheimer's Disease: Triazinones As BACE-1 and GSK-3β Inhibitors Angewandte Chemie (International Ed. in English). Jan, 2015 | Pubmed ID: 25504761 Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase Angewandte Chemie (International Ed. in English). Jan, 2015 | Pubmed ID: 25395373 3-Aminoazetidin-2-one Derivatives As N-acylethanolamine Acid Amidase (NAAA) Inhibitors Suitable for Systemic Administration ChemMedChem. Jul, 2014 | Pubmed ID: 24828120 A Glycosylated, Labionin-containing Lanthipeptide with Marked Antinociceptive Activity ACS Chemical Biology. Feb, 2014 | Pubmed ID: 24191663 CCL5-glutamate Interaction in Central Nervous System: Early and Acute Presynaptic Defects in EAE Mice Neuropharmacology. Dec, 2013 | Pubmed ID: 23958452 Increased Excitability in Tat-transgenic Mice: Role of Tat in HIV-related Neurological Disorders Neurobiology of Disease. Jul, 2013 | Pubmed ID: 23454193 Compensatory Molecular and Functional Mechanisms in Nervous System of the Grm1(crv4) Mouse Lacking the MGlu1 Receptor: a Model for Motor Coordination Deficits Cerebral Cortex (New York, N.Y. : 1991). Sep, 2013 | Pubmed ID: 22791805 Presynaptic MGlu7 Receptors Control GABA Release in Mouse Hippocampus Neuropharmacology. Mar, 2013 | Pubmed ID: 22564442 Anxiety-like Behavior of Prenatally Stressed Rats is Associated with a Selective Reduction of Glutamate Release in the Ventral Hippocampus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2012 | Pubmed ID: 23197707 In vitro Exposure to Nicotine Induces Endocytosis of Presynaptic AMPA Receptors Modulating Dopamine Release in Rat Nucleus Accumbens Nerve Terminals Neuropharmacology. Oct, 2012 | Pubmed ID: 22771975 RANTES-mediated Control of Excitatory Amino Acid Release in Mouse Spinal Cord Journal of Neurochemistry. May, 2012 | Pubmed ID: 22385043 Detection of Etiological Agents of Malaria in Howler Monkeys from Atlantic Forests, Rescued in Regions of São Paulo City, Brazil Journal of Medical Primatology. Dec, 2011 | Pubmed ID: 21933192 Hippocampal AMPA Autoreceptors Positively Coupled to NMDA Autoreceptors Traffic in a Constitutive Manner and Undergo Adaptative Changes Following Enriched Environment Training Neuropharmacology. Dec, 2011 | Pubmed ID: 21820454 Pre-synaptic Glycine GlyT1 Transporter--NMDA Receptor Interaction: Relevance to NMDA Autoreceptor Activation in the Presence of Mg2+ Ions Journal of Neurochemistry. May, 2011 | Pubmed ID: 21348870 Improving Processes for Blood Factor Products: from Blood Bank to Hospital Pharmacy American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists. Feb, 2010 | Pubmed ID: 20133529 The HIV-1 Viral Protein Tat Increases Glutamate and Decreases GABA Exocytosis from Human and Mouse Neocortical Nerve Endings Cerebral Cortex (New York, N.Y. : 1991). Aug, 2010 | Pubmed ID: 20034999 Natural Plasmodium Infections in Brazilian Wild Monkeys: Reservoirs for Human Infections? Acta Tropica. Aug, 2008 | Pubmed ID: 18620330 Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase Elisa Romeo1, Silvia Pontis1, Stefano Ponzano1, Fabiola Bonezzi1, Marco Migliore1, Simona Di Martino1, Maria Summa1, Daniele Piomelli1,2 1Drug Discovery and Development, Istituto Italiano di Tecnologia, 2Departments of Anatomy and Neurobiology, Pharmacology, and Biological Chemistry, University of California, Irvine School of Medicine JoVE 54652 Bioquímica
Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase Elisa Romeo1, Silvia Pontis1, Stefano Ponzano1, Fabiola Bonezzi1, Marco Migliore1, Simona Di Martino1, Maria Summa1, Daniele Piomelli1,2 1Drug Discovery and Development, Istituto Italiano di Tecnologia, 2Departments of Anatomy and Neurobiology, Pharmacology, and Biological Chemistry, University of California, Irvine School of Medicine JoVE 54652 Bioquímica