James Fraser Department of Veterinary and Biomedical Sciences The Pennsylvania State University Biography Publications Institution JoVE Articles James Fraser has not added a biography. If you are James Fraser and would like to personalize this page please email our Author Liaison for assistance. Publications Calcium-dependent Nedd4-2 Upregulation Mediates Degradation of the Cardiac Sodium Channel Nav1.5: Implications for Heart Failure Acta Physiologica (Oxford, England). Mar, 2017 | Pubmed ID: 28296171 Complex Multi-enhancer Contacts Captured by Genome Architecture Mapping Nature. Mar, 2017 | Pubmed ID: 28273065 QUESTION 2: Does Prophylactic Nystatin Prevent Invasive Fungal Infections in Immunocompetent Critically Ill Children on Broad-spectrum Antibiotics? Archives of Disease in Childhood. Mar, 2017 | Pubmed ID: 28213455 The 2.0 Å X-ray Structure for Yeast Acetohydroxyacid Synthase Provides New Insights into Its Cofactor and Quaternary Structure Requirements PloS One. 2017 | Pubmed ID: 28178302 Cytidine Deaminase Efficiency of the Lentiviral Viral Restriction Factor APOBEC3C Correlates with Dimerization Nucleic Acids Research. Feb, 2017 | Pubmed ID: 28158858 GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus Neoformans The Journal of Biological Chemistry. Feb, 2017 | Pubmed ID: 28062578 Conformational Variation of Proteins at Room Temperature is Not Dominated by Radiation Damage Journal of Synchrotron Radiation. Jan, 2017 | Pubmed ID: 28009548 Men with Duchenne Muscular Dystrophy and End of Life Planning Neuromuscular Disorders : NMD. Jan, 2017 | Pubmed ID: 27816330 Calculating the Cost and Risk of Comorbidities in Total Joint Arthroplasty in the United States The Journal of Arthroplasty. Feb, 2017 | Pubmed ID: 27623745 International Rates of Patellar Resurfacing in Primary Total Knee Arthroplasty, 2004-2014 The Journal of Arthroplasty. Jan, 2017 | Pubmed ID: 27421587 The Halo Effect: An Unintended Benefit of Care Pathways The Journal of Knee Surgery. Mar, 2017 | Pubmed ID: 27362923 Immunogenicity of a Peptide-based Anti-IgE Conjugate Vaccine in Non-human Primates Immunity, Inflammation and Disease. Jun, 2016 | Pubmed ID: 27957325 Cell-type-specific Expression of NFIX in the Developing and Adult Cerebellum Brain Structure & Function. Nov, 2016 | Pubmed ID: 27878595 Corrigendum: Determining Crystal Structures Through Crowdsourcing and Coursework Nature Communications. Oct, 2016 | Pubmed ID: 27779204 Disruption of De Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus Neoformans ACS Infectious Diseases. Sep, 2016 | Pubmed ID: 27759389 Targeted Genome Editing Via CRISPR in the Pathogen Cryptococcus Neoformans PloS One. 2016 | Pubmed ID: 27711143 Automated Structure Refinement of Macromolecular Assemblies from Cryo-EM Maps Using Rosetta ELife. Sep, 2016 | Pubmed ID: 27669148 Chemical Inhibitors of Non-Homologous End Joining Increase Targeted Construct Integration in Cryptococcus Neoformans PloS One. 2016 | Pubmed ID: 27643854 Determining Crystal Structures Through Crowdsourcing and Coursework Nature Communications. Sep, 2016 | Pubmed ID: 27633552 From Deep TLS Validation to Ensembles of Atomic Models Built from Elemental Motions. Addenda and Corrigendum Acta Crystallographica. Section D, Structural Biology. Sep, 2016 | Pubmed ID: 27599739 Patient Perception of Value in Bundled Payments for Total Joint Arthroplasty The Journal of Arthroplasty. Dec, 2016 | Pubmed ID: 27378636 SCIENTIFIC COMMUNITY. Preprints for the Life Sciences Science (New York, N.Y.). May, 2016 | Pubmed ID: 27199406 Benchmarking in Australia Using the International Foundations of Medicine Clinical Science Examination The Medical Journal of Australia. May, 2016 | Pubmed ID: 27169965 Determination of Ubiquitin Fitness Landscapes Under Different Chemical Stresses in a Classroom Setting ELife. Apr, 2016 | Pubmed ID: 27111525 Measuring and Modeling Diffuse Scattering in Protein X-ray Crystallography Proceedings of the National Academy of Sciences of the United States of America. Apr, 2016 | Pubmed ID: 27035972 Metapopulation Viability of an Endangered Shorebird Depends on Dispersal and Human-created Habitats: Piping Plovers (Charadrius Melodus) and Prairie Rivers Movement Ecology. 2016 | Pubmed ID: 26981249 Data Publication with the Structural Biology Data Grid Supports Live Analysis Nature Communications. Mar, 2016 | Pubmed ID: 26947396 Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase Angewandte Chemie (International Ed. in English). Mar, 2016 | Pubmed ID: 26924714 High-density Grids for Efficient Data Collection from Multiple Crystals Acta Crystallographica. Section D, Structural Biology. Jan, 2016 | Pubmed ID: 26894529 Whole Genome Comparison Reveals High Levels of Inbreeding and Strain Redundancy Across the Spectrum of Commercial Wine Strains of Saccharomyces Cerevisiae G3 (Bethesda, Md.). Apr, 2016 | Pubmed ID: 26869621 CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites Journal of Molecular Biology. Feb, 2016 | Pubmed ID: 26854760 Antibacterial and Antifungal Screening of Natural Products Sourced from Australian Fungi and Characterisation of Pestalactams D-F Phytochemistry. Apr, 2016 | Pubmed ID: 26743853 Automated 3D Bone Ablation with 1,070 nm Ytterbium-doped Fiber Laser Enabled by Inline Coherent Imaging Lasers in Surgery and Medicine. Mar, 2016 | Pubmed ID: 26718116 Impact of Neuraminidase Inhibitors on Influenza A(H1N1)pdm09-related Pneumonia: an Individual Participant Data Meta-analysis Influenza and Other Respiratory Viruses. May, 2016 | Pubmed ID: 26602067 The Morbidity and Mortality Meeting: Time for a Different Approach? Archives of Disease in Childhood. Jan, 2016 | Pubmed ID: 26566689 The RyR2-P2328S Mutation Downregulates Nav1.5 Producing Arrhythmic Substrate in Murine Ventricles Pflugers Archiv : European Journal of Physiology. Apr, 2016 | Pubmed ID: 26545784 Hierarchical Folding and Reorganization of Chromosomes Are Linked to Transcriptional Changes in Cellular Differentiation Molecular Systems Biology. Dec, 2015 | Pubmed ID: 26700852 High-resolution Structures of the M2 Channel from Influenza A Virus Reveal Dynamic Pathways for Proton Stabilization and Transduction Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015 | Pubmed ID: 26578770 Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using QFit PLoS Computational Biology. Oct, 2015 | Pubmed ID: 26506617 Polyploid Titan Cells Produce Haploid and Aneuploid Progeny to Promote Stress Adaptation MBio. Oct, 2015 | Pubmed ID: 26463162 Mapping the Conformational Landscape of a Dynamic Enzyme by Multitemperature and XFEL Crystallography ELife. Sep, 2015 | Pubmed ID: 26422513 Comparative Genomics of Non-pseudomonal Bacterial Species Colonising Paediatric Cystic Fibrosis Patients PeerJ. 2015 | Pubmed ID: 26401445 Whole-genome Sequencing Identifies EN1 As a Determinant of Bone Density and Fracture Nature. Oct, 2015 | Pubmed ID: 26367794 Flemingin-Type Prenylated Chalcones from the Sarawak Rainforest Plant Desmodium Congestum Journal of Natural Products. Aug, 2015 | Pubmed ID: 26284978 EMRinger: Side Chain-directed Model and Map Validation for 3D Cryo-electron Microscopy Nature Methods. Oct, 2015 | Pubmed ID: 26280328 From Deep TLS Validation to Ensembles of Atomic Models Built from Elemental Motions Acta Crystallographica. Section D, Biological Crystallography. Aug, 2015 | Pubmed ID: 26249348 Predicting X-ray Diffuse Scattering from Translation-libration-screw Structural Ensembles Acta Crystallographica. Section D, Biological Crystallography. Aug, 2015 | Pubmed ID: 26249347 An Overview of Genome Organization and How We Got There: from FISH to Hi-C Microbiology and Molecular Biology Reviews : MMBR. Sep, 2015 | Pubmed ID: 26223848 Complete Genome Sequence of Sporisorium Scitamineum and Biotrophic Interaction Transcriptome with Sugarcane PloS One. 2015 | Pubmed ID: 26065709 One Crystal, Two Temperatures: Cryocooling Penalties Alter Ligand Binding to Transient Protein Sites Chembiochem : a European Journal of Chemical Biology. Jul, 2015 | Pubmed ID: 26032594 Negative Epistasis and Evolvability in TEM-1 β-Lactamase--The Thin Line Between an Enzyme's Conformational Freedom and Disorder Journal of Molecular Biology. Jul, 2015 | Pubmed ID: 26004540 Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity Cell Reports. May, 2015 | Pubmed ID: 25981045 A Genomic Safe Haven for Mutant Complementation in Cryptococcus Neoformans PloS One. 2015 | Pubmed ID: 25856300 Integrative, Dynamic Structural Biology at Atomic Resolution--it's About Time Nature Methods. Apr, 2015 | Pubmed ID: 25825836 Differential Regenerative Capacity of Neonatal Mouse Hearts After Cryoinjury Developmental Biology. Mar, 2015 | Pubmed ID: 25555840 Keep on Moving: Discovering and Perturbing the Conformational Dynamics of Enzymes Accounts of Chemical Research. Feb, 2015 | Pubmed ID: 25539415 Wear and Loosening in Total Knee Arthroplasty: a Quick Review The Journal of Knee Surgery. Apr, 2015 | Pubmed ID: 25539400 The Gown-glove Interface Is a Source of Contamination: A Comparative Study Clinical Orthopaedics and Related Research. Jul, 2015 | Pubmed ID: 25488405 Conformational Dynamics of a Crystalline Protein from Microsecond-scale Molecular Dynamics Simulations and Diffuse X-ray Scattering Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25453071 The Determinants of Transverse Tubular Volume in Resting Skeletal Muscle The Journal of Physiology. Dec, 2014 | Pubmed ID: 25384782 Discovery and Characterization of Gut Microbiota Decarboxylases That Can Produce the Neurotransmitter Tryptamine Cell Host & Microbe. Oct, 2014 | Pubmed ID: 25263219 Understanding Why Children Die in High-income Countries Lancet (London, England). Sep, 2014 | Pubmed ID: 25209491 Patterns of Child Death in England and Wales Lancet (London, England). Sep, 2014 | Pubmed ID: 25209490 Learning from Child Death Review in the USA, England, Australia, and New Zealand Lancet (London, England). Sep, 2014 | Pubmed ID: 25209489 Child Death in High-income Countries Lancet (London, England). Sep, 2014 | Pubmed ID: 25209471 Increased Transfusion-free Survival Following Auxiliary Pig Liver Xenotransplantation Xenotransplantation. Sep-Oct, 2014 | Pubmed ID: 25130043 E Pluribus Unum, No More: from One Crystal, Many Conformations Current Opinion in Structural Biology. Oct, 2014 | Pubmed ID: 25113271 Cryptococcus Neoformans and Cryptococcus Gattii, the Etiologic Agents of Cryptococcosis Cold Spring Harbor Perspectives in Medicine. Jul, 2014 | Pubmed ID: 24985132 Incorporation of Protein Flexibility and Conformational Energy Penalties in Docking Screens to Improve Ligand Discovery Nature Chemistry. Jul, 2014 | Pubmed ID: 24950326 Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR Structure (London, England : 1993). Jun, 2014 | Pubmed ID: 24882744 Analysis of the Genome and Transcriptome of Cryptococcus Neoformans Var. Grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence Attenuation PLoS Genetics. Apr, 2014 | Pubmed ID: 24743168 Mkk4 is a Negative Regulator of the Transforming Growth Factor Beta 1 Signaling Associated with Atrial Remodeling and Arrhythmogenesis with Age Journal of the American Heart Association. Apr, 2014 | Pubmed ID: 24721794 Measurement and Interpretation of Electrocardiographic QT Intervals in Murine Hearts American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2014 | Pubmed ID: 24705556 Teaching and Physics Education Research: Bridging the Gap Reports on Progress in Physics. Physical Society (Great Britain). Mar, 2014 | Pubmed ID: 24595011 Multiple Nuclear Localization Signals Mediate Nuclear Localization of the GATA Transcription Factor AreA Eukaryotic Cell. Apr, 2014 | Pubmed ID: 24562911 A Conceptual Model of the Role of Complexity in the Care of Patients with Multiple Chronic Conditions Medical Care. Mar, 2014 | Pubmed ID: 24561762 Antimicrobial Distribution from Local Delivery Depends on Dose : a Pilot Study with MRI Clinical Orthopaedics and Related Research. Nov, 2014 | Pubmed ID: 24510357 Diffuse X-ray Scattering to Model Protein Motions Structure (London, England : 1993). Feb, 2014 | Pubmed ID: 24507780 Functional Consequences of NKCC2 Splice Isoforms: Insights from a Xenopus Oocyte Model American Journal of Physiology. Renal Physiology. Apr, 2014 | Pubmed ID: 24477685 Integrated Description of Protein Dynamics from Room-temperature X-ray Crystallography and NMR Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24474795 Protein Structural Ensembles Are Revealed by Redefining X-ray Electron Density Noise Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014 | Pubmed ID: 24363322 Improving the Practice of Child Death Overview Panels: a Paediatric Perspective Archives of Disease in Childhood. Mar, 2014 | Pubmed ID: 24255566 The SCN5A Mutation A1180V is Associated with Electrocardiographic Features of LQT3 Pediatric Cardiology. Feb, 2014 | Pubmed ID: 23963187 Balancing Stability and Flexibility Within the Genome of the Pathogen Cryptococcus Neoformans PLoS Pathogens. 2013 | Pubmed ID: 24348244 Repurposing CRISPR/Cas9 for in Situ Functional Assays Genes & Development. Dec, 2013 | Pubmed ID: 24298059 Purification, Crystallization and Preliminary X-ray Analysis of Adenylosuccinate Synthetase from the Fungal Pathogen Cryptococcus Neoformans Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Sep, 2013 | Pubmed ID: 23989157 From Structure to Systems: High-resolution, Quantitative Genetic Analysis of RNA Polymerase II Cell. Aug, 2013 | Pubmed ID: 23932120 Automated Identification of Functional Dynamic Contact Networks from X-ray Crystallography Nature Methods. Sep, 2013 | Pubmed ID: 23913260 Secondary Metabolites of the Sponge-derived Fungus Acremonium Persicinum Journal of Natural Products. Aug, 2013 | Pubmed ID: 23883432 Determinants of Myocardial Conduction Velocity: Implications for Arrhythmogenesis Frontiers in Physiology. 2013 | Pubmed ID: 23825462 A Polymer Model Explains the Complexity of Large-scale Chromatin Folding Nucleus (Austin, Tex.). Jul-Aug, 2013 | Pubmed ID: 23823730 Is the Nickel-dependent Urease Complex of Cryptococcus the Pathogen's Achilles' Heel? MBio. Jun, 2013 | Pubmed ID: 23800398 Phase I Dose Escalation Study of Bortezomib in Combination with Lenalidomide in Patients with Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) Leukemia Research. Sep, 2013 | Pubmed ID: 23773898 "It's Common Sense That It's Wrong": Young People's Perceptions and Experiences of Cyberbullying Cyberpsychology, Behavior and Social Networking. Nov, 2013 | Pubmed ID: 23745618 Loss of Nav1.5 Expression and Function in Murine Atria Containing the RyR2-P2328S Gain-of-function Mutation Cardiovascular Research. Sep, 2013 | Pubmed ID: 23723061 Deep Nonlinear Ablation of Silicon with a Quasi-continuous Wave Fiber Laser at 1070 Nm Optics Letters. Jun, 2013 | Pubmed ID: 23722748 Nitrogen Regulation of Virulence in Clinically Prevalent Fungal Pathogens FEMS Microbiology Letters. Aug, 2013 | Pubmed ID: 23701678 Characterization of the Complete Uric Acid Degradation Pathway in the Fungal Pathogen Cryptococcus Neoformans PloS One. 2013 | Pubmed ID: 23667704 Extracellular Magnesium and Calcium Reduce Myotonia in ClC-1 Inhibited Rat Muscle Neuromuscular Disorders : NMD. Jun, 2013 | Pubmed ID: 23623567 Reactive Oxygen Species Homeostasis and Virulence of the Fungal Pathogen Cryptococcus Neoformans Requires an Intact Proline Catabolism Pathway Genetics. Jun, 2013 | Pubmed ID: 23564202 Comparative Genomics of Serial Isolates of Cryptococcus Neoformans Reveals Gene Associated With Carbon Utilization and Virulence G3 (Bethesda, Md.). Apr, 2013 | Pubmed ID: 23550133 Appropriateness of Imaging in Canada Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes. May, 2013 | Pubmed ID: 23528386 A Model of the Large-scale Organization of Chromatin Biochemical Society Transactions. Apr, 2013 | Pubmed ID: 23514144 Flexible Backbone Sampling Methods to Model and Design Protein Alternative Conformations Methods in Enzymology. 2013 | Pubmed ID: 23422426 Ploidy Variation As an Adaptive Mechanism in Human Pathogenic Fungi Seminars in Cell & Developmental Biology. Apr, 2013 | Pubmed ID: 23380396 From Systems to Structure: Bridging Networks and Mechanism Molecular Cell. Jan, 2013 | Pubmed ID: 23352243 Sulfonylureas Have Antifungal Activity and Are Potent Inhibitors of Candida Albicans Acetohydroxyacid Synthase Journal of Medicinal Chemistry. Jan, 2013 | Pubmed ID: 23237384 Conduction Slowing Contributes to Spontaneous Ventricular Arrhythmias in Intrinsically Active Murine RyR2-P2328S Hearts Journal of Cardiovascular Electrophysiology. Feb, 2013 | Pubmed ID: 23131176 De Novo GTP Biosynthesis is Critical for Virulence of the Fungal Pathogen Cryptococcus Neoformans PLoS Pathogens. 2012 | Pubmed ID: 23071437 Complexity of Chromatin Folding is Captured by the Strings and Binders Switch Model Proceedings of the National Academy of Sciences of the United States of America. Oct, 2012 | Pubmed ID: 22988072 In Support of the BMRB Nature Structural & Molecular Biology. Sep, 2012 | Pubmed ID: 22955930 Convergent Adaptations: Bitter Manioc Cultivation Systems in Fertile Anthropogenic Dark Earths and Floodplain Soils in Central Amazonia PloS One. 2012 | Pubmed ID: 22952727 CheShift-2 Resolves a Local Inconsistency Between Two X-ray Crystal Structures Journal of Biomolecular NMR. Oct, 2012 | Pubmed ID: 22945426 A Torrent of Data: Mapping Chromatin Organization Using 5C and High-throughput Sequencing Methods in Enzymology. 2012 | Pubmed ID: 22929767 Systematic Functional Prioritization of Protein Posttranslational Modifications Cell. Jul, 2012 | Pubmed ID: 22817900 Anti-interleukin-10R1 Monoclonal Antibody Enhances Bacillus Calmette-Guérin Induced T-helper Type 1 Immune Responses and Antitumor Immunity in a Mouse Orthotopic Model of Bladder Cancer The Journal of Urology. Jun, 2012 | Pubmed ID: 22503050 Characterization of an Nmr Homolog That Modulates GATA Factor-mediated Nitrogen Metabolite Repression in Cryptococcus Neoformans PloS One. 2012 | Pubmed ID: 22470421 Control of Protein Signaling Using a Computationally Designed GTPase/GEF Orthogonal Pair Proceedings of the National Academy of Sciences of the United States of America. Apr, 2012 | Pubmed ID: 22403064 A Unique Chromosomal Rearrangement in the Cryptococcus Neoformans Var. Grubii Type Strain Enhances Key Phenotypes Associated with Virulence MBio. 2012 | Pubmed ID: 22375073 Discovery of a Modified Tetrapolar Sexual Cycle in Cryptococcus Amylolentus and the Evolution of MAT in the Cryptococcus Species Complex PLoS Genetics. 2012 | Pubmed ID: 22359516 Quantifying and Comparing Torsional Strains After Olecranon Plating Injury. Jun, 2012 | Pubmed ID: 22348953 Microevolution of Cryptococcus Neoformans Driven by Massive Tandem Gene Amplification Molecular Biology and Evolution. Aug, 2012 | Pubmed ID: 22334577 Altered Sinoatrial Node Function and Intra-atrial Conduction in Murine Gain-of-function Scn5a+/ΔKPQ Hearts Suggest an Overlap Syndrome American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2012 | Pubmed ID: 22287583 Real-time Guidance of Thermal and Ultrashort Pulsed Laser Ablation in Hard Tissue Using Inline Coherent Imaging Lasers in Surgery and Medicine. Mar, 2012 | Pubmed ID: 22241665 Dimethyl Sulphoxide Addition or Withdrawal Causes Biphasic Volume Changes and Its Withdrawal Causes T-system Vacuolation in Skeletal Muscle The Journal of Physiology. Nov, 2011 | Pubmed ID: 22086252 Three-dimensional Modeling of Chromatin Structure from Interaction Frequency Data Using Markov Chain Monte Carlo Sampling BMC Bioinformatics. Oct, 2011 | Pubmed ID: 22026390 Reciprocal Dihydropyridine and Ryanodine Receptor Interactions in Skeletal Muscle Activation Journal of Muscle Research and Cell Motility. Nov, 2011 | Pubmed ID: 21993921 Accessing Protein Conformational Ensembles Using Room-temperature X-ray Crystallography Proceedings of the National Academy of Sciences of the United States of America. Sep, 2011 | Pubmed ID: 21918110 A Diverse Population of Cryptococcus Gattii Molecular Type VGIII in Southern Californian HIV/AIDS Patients PLoS Pathogens. Sep, 2011 | Pubmed ID: 21909264 An Analysis of the Relationships Between Subthreshold Electrical Properties and Excitability in Skeletal Muscle The Journal of General Physiology. Jul, 2011 | Pubmed ID: 21670208 Relationships Between Resting Conductances, Excitability, and T-system Ionic Homeostasis in Skeletal Muscle The Journal of General Physiology. Jul, 2011 | Pubmed ID: 21670205 Nitrogen Metabolite Repression of Metabolism and Virulence in the Human Fungal Pathogen Cryptococcus Neoformans Genetics. Jun, 2011 | Pubmed ID: 21441208 Increasing Prevalence of Domiciliary Ventilation: Changes in Service Demand and Provision in the South West of the UK European Journal of Pediatrics. Sep, 2011 | Pubmed ID: 21360027 Repetitive Flood Victims and Acceptance of FEMA Mitigation Offers: an Analysis with Community-system Policy Implications Disasters. Jul, 2011 | Pubmed ID: 21272056 The Underwater Photic Environment of Cape Maclear, Lake Malawi: Comparison Between Rock- and Sand-bottom Habitats and Implications for Cichlid Fish Vision The Journal of Experimental Biology. Feb, 2011 | Pubmed ID: 21228208 Mining Electron Density for Functionally Relevant Protein Polysterism in Crystal Structures Cellular and Molecular Life Sciences : CMLS. Jun, 2011 | Pubmed ID: 21190057 Acute Atrial Arrhythmogenicity and Altered Ca(2+) Homeostasis in Murine RyR2-P2328S Hearts Cardiovascular Research. Mar, 2011 | Pubmed ID: 20621925 The Tumor-associated EpCAM Regulates Morphogenetic Movements Through Intracellular Signaling The Journal of Cell Biology. Nov, 2010 | Pubmed ID: 20974811 Computing Chromosome Conformation Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20827597 Crystallization and Preliminary X-ray Analysis of Mycophenolic Acid-resistant and Mycophenolic Acid-sensitive Forms of IMP Dehydrogenase from the Human Fungal Pathogen Cryptococcus Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Sep, 2010 | Pubmed ID: 20823538 Automated Electron-density Sampling Reveals Widespread Conformational Polymorphism in Proteins Protein Science : a Publication of the Protein Society. Jul, 2010 | Pubmed ID: 20499387 America's Fertile Frontier: How America Surpassed Britain in the Development and Growth of Plastic Surgery During the Interwar Years of 1920-1940 Annals of Plastic Surgery. May, 2010 | Pubmed ID: 20395812 Comprehensive Management of Hot-press Hand Injuries: Long-term Outcomes Following Reconstruction and Rehabilitation Annals of Plastic Surgery. May, 2010 | Pubmed ID: 20395811 Saturation of the Photoluminescence at Few-exciton Levels in a Single-walled Carbon Nanotube Under Ultrafast Excitation Physical Review Letters. Jan, 2010 | Pubmed ID: 20366391 In Situ 24 KHz Coherent Imaging of Morphology Change in Laser Percussion Drilling Optics Letters. Mar, 2010 | Pubmed ID: 20195306 Accidental Ingestion of Dosulepin Presenting As Atrial Flutter in a Child European Journal of Pediatrics. Jan, 2010 | Pubmed ID: 19347362 Hidden Alternative Structures of Proline Isomerase Essential for Catalysis Nature. Dec, 2009 | Pubmed ID: 19956261 Prevalence of Antibodies to West Nile Virus and Other Arboviruses Among Crested Caracaras (Caracara Cheriway) in Florida Journal of Wildlife Diseases. Jul, 2009 | Pubmed ID: 19617494 Chromatin Conformation Signatures of Cellular Differentiation Genome Biology. 2009 | Pubmed ID: 19374771 Contrast Improvement in Fourier-domain Optical Coherence Tomography Through Time Gating Journal of the Optical Society of America. A, Optics, Image Science, and Vision. Apr, 2009 | Pubmed ID: 19340272 Sexual Reproduction and Dimorphism in the Pathogenic Basidiomycetes FEMS Yeast Research. Mar, 2009 | Pubmed ID: 19220864 Control of Cell Volume in Skeletal Muscle Biological Reviews of the Cambridge Philosophical Society. Feb, 2009 | Pubmed ID: 19133959 Pharmacological Characterization of a Small Molecule Inhibitor of C-Jun Kinase American Journal of Physiology. Endocrinology and Metabolism. Nov, 2008 | Pubmed ID: 18728225 Transitions in Sexuality: Recapitulation of an Ancestral Tri- and Tetrapolar Mating System in Cryptococcus Neoformans Eukaryotic Cell. Oct, 2008 | Pubmed ID: 18723606 Translational Imaging Studies of Cortical Spreading Depression in Experimental Models for Migraine Aura Expert Review of Neurotherapeutics. May, 2008 | Pubmed ID: 18457533 Extracellular Charge Adsorption Influences Intracellular Electrochemical Homeostasis in Amphibian Skeletal Muscle Biophysical Journal. Jun, 2008 | Pubmed ID: 18310253 High Speed in Situ Depth Profiling of Ultrafast Micromachining Optics Express. Nov, 2007 | Pubmed ID: 19550777 Similarities and Contrasts in Ryanodine Receptor Localization and Function in Osteoclasts and Striated Muscle Cells Annals of the New York Academy of Sciences. Nov, 2007 | Pubmed ID: 18083933 Time-gated Fourier-domain Optical Coherence Tomography Optics Letters. Nov, 2007 | Pubmed ID: 18026299 Birnbaum LM, Filion KB, Joyal D, Eisenberg MJ. Second Reading of Coronary Angiograms by Radiologists. Can J Cardiol 2006;22(14):1217-1221 The Canadian Journal of Cardiology. Sep, 2007 | Pubmed ID: 17907348 Immunoglobulin-like Domains on Bacteriophage: Weapons of Modest Damage? Current Opinion in Microbiology. Aug, 2007 | Pubmed ID: 17765600 First Contemporary Case of Human Infection with Cryptococcus Gattii in Puget Sound: Evidence for Spread of the Vancouver Island Outbreak Journal of Clinical Microbiology. Sep, 2007 | Pubmed ID: 17596366 An Atypical Receiver Domain Controls the Dynamic Polar Localization of the Myxococcus Xanthus Social Motility Protein FrzS Molecular Microbiology. Jul, 2007 | Pubmed ID: 17573816 Distribution Patterns of Estrogen Receptor Alpha and Beta in the Human Cortex and Hippocampus During Development and Adulthood The Journal of Comparative Neurology. Aug, 2007 | Pubmed ID: 17570500 A Quantitative Analysis of the Effect of Cycle Length on Arrhythmogenicity in Hypokalaemic Langendorff-perfused Murine Hearts Pflugers Archiv : European Journal of Physiology. Sep, 2007 | Pubmed ID: 17437126 Evolution of the Mating Type Locus: Insights Gained from the Dimorphic Primary Fungal Pathogens Histoplasma Capsulatum, Coccidioides Immitis, and Coccidioides Posadasii Eukaryotic Cell. Apr, 2007 | Pubmed ID: 17337636 Alterations in Triad Ultrastructure Following Repetitive Stimulation and Intracellular Changes Associated with Exercise in Amphibian Skeletal Muscle Journal of Muscle Research and Cell Motility. 2007 | Pubmed ID: 17333488 The Contribution of Refractoriness to Arrhythmic Substrate in Hypokalemic Langendorff-perfused Murine Hearts Pflugers Archiv : European Journal of Physiology. May, 2007 | Pubmed ID: 17295037 Heat-induced Dimerization of BCL-xL Through Alpha-helix Swapping Biochemistry. Jan, 2007 | Pubmed ID: 17223694 Quantitative Techniques for Steady-state Calculation and Dynamic Integrated Modelling of Membrane Potential and Intracellular Ion Concentrations Progress in Biophysics and Molecular Biology. Jul, 2007 | Pubmed ID: 17129600 Biochemical Signal Detection in Miniaturized Fluidic Systems by Integrated Microresonator Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2006 | Pubmed ID: 17946809 Membrane Potentials in Rana Temporaria Muscle Fibres in Strongly Hypertonic Solutions Journal of Muscle Research and Cell Motility. 2006 | Pubmed ID: 17051346 Characterization of Estrogen Receptors Alpha and Beta in Uterine Leiomyoma Cells Fertility and Sterility. Dec, 2006 | Pubmed ID: 17011556 Pyridine-2-propanoic Acids: Discovery of Dual PPARalpha/gamma Agonists As Antidiabetic Agents Bioorganic & Medicinal Chemistry Letters. Dec, 2006 | Pubmed ID: 16979341 Pyridine-3-propanoic Acids: Discovery of Dual PPARalpha/gamma Agonists As Antidiabetic Agents Bioorganic & Medicinal Chemistry Letters. Dec, 2006 | Pubmed ID: 16973358 Alterations in Calcium Homeostasis Reduce Membrane Excitability in Amphibian Skeletal Muscle Pflugers Archiv : European Journal of Physiology. Nov, 2006 | Pubmed ID: 16955310 Recent Evolution of the Human Pathogen Cryptococcus Neoformans by Intervarietal Transfer of a 14-gene Fragment Molecular Biology and Evolution. Oct, 2006 | Pubmed ID: 16870684 Parametric Cascade Downconverter for Intense Ultrafast Mid-infrared Generation Beyond the Manley-Rowe Limit Applied Optics. Jun, 2006 | Pubmed ID: 16761052 Yeast Diversity Sampling on the San Juan Islands Reveals No Evidence for the Spread of the Vancouver Island Cryptococcus Gattii Outbreak to This Locale FEMS Yeast Research. Jun, 2006 | Pubmed ID: 16696658 Ig-like Domains on Bacteriophages: a Tale of Promiscuity and Deceit Journal of Molecular Biology. Jun, 2006 | Pubmed ID: 16631788 The Influence of Intracellular Lactate and H+ on Cell Volume in Amphibian Skeletal Muscle The Journal of Physiology. Jun, 2006 | Pubmed ID: 16613877 Effect of Repetitive Stimulation on Cell Volume and Its Relationship to Membrane Potential in Amphibian Skeletal Muscle Pflugers Archiv : European Journal of Physiology. May, 2006 | Pubmed ID: 16404610 Same-sex Mating and the Origin of the Vancouver Island Cryptococcus Gattii Outbreak Nature. Oct, 2005 | Pubmed ID: 16222245 Nuclear Accumulation of the GATA Factor AreA in Response to Complete Nitrogen Starvation by Regulation of Nuclear Export Eukaryotic Cell. Oct, 2005 | Pubmed ID: 16215172 Chromosomal Sex-determining Regions in Animals, Plants and Fungi Current Opinion in Genetics & Development. Dec, 2005 | Pubmed ID: 16182521 Deciphering the Model Pathogenic Fungus Cryptococcus Neoformans Nature Reviews. Microbiology. Oct, 2005 | Pubmed ID: 16132036 Clinical and Environmental Isolates of Cryptococcus Gattii from Australia That Retain Sexual Fecundity Eukaryotic Cell. Aug, 2005 | Pubmed ID: 16087746 Chromosomal Translocation and Segmental Duplication in Cryptococcus Neoformans Eukaryotic Cell. Feb, 2005 | Pubmed ID: 15701802 The Genome of the Basidiomycetous Yeast and Human Pathogen Cryptococcus Neoformans Science (New York, N.Y.). Feb, 2005 | Pubmed ID: 15653466 Slow Volume Transients in Amphibian Skeletal Muscle Fibres Studied in Hypotonic Solutions The Journal of Physiology. Apr, 2005 | Pubmed ID: 15649980 The Effect of Intracellular Acidification on the Relationship Between Cell Volume and Membrane Potential in Amphibian Skeletal Muscle The Journal of Physiology. Mar, 2005 | Pubmed ID: 15618273 2-Alkoxydihydrocinnamates As PPAR Agonists. Activity Modulation by the Incorporation of Phenoxy Substituents Bioorganic & Medicinal Chemistry Letters. Jan, 2005 | Pubmed ID: 15582409 Detubulation Experiments Localise Delayed Rectifier Currents to the Surface Membrane of Amphibian Skeletal Muscle Fibres Journal of Muscle Research and Cell Motility. 2004 | Pubmed ID: 15548868 Detubulation Abolishes Membrane Potential Stabilization in Amphibian Skeletal Muscle Journal of Muscle Research and Cell Motility. 2004 | Pubmed ID: 15548867 Convergent Evolution of Chromosomal Sex-determining Regions in the Animal and Fungal Kingdoms PLoS Biology. Dec, 2004 | Pubmed ID: 15538538 Improving Treatment Services for Substance Abusers with Comorbid Depression The American Journal on Addictions. May-Jun, 2004 | Pubmed ID: 15370949 Coherent Vibrational Climbing in Carboxyhemoglobin Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004 | Pubmed ID: 15319472 PAK Kinases Ste20 and Pak1 Govern Cell Polarity at Different Stages of Mating in Cryptococcus Neoformans Molecular Biology of the Cell. Oct, 2004 | Pubmed ID: 15282344 A Quantitative Analysis of Cell Volume and Resting Potential Determination and Regulation in Excitable Cells The Journal of Physiology. Sep, 2004 | Pubmed ID: 15243134 Venous Protocols, Techniques, and Interpretations of the Upper and Lower Extremities Radiologic Clinics of North America. Mar, 2004 | Pubmed ID: 15136017 Isolering, karakterisering och rening av makrofager från vävnader som påverkas av fetma-relaterade Inflammation Joselyn N. Allen1, Adwitia Dey1, Ruth Nissly2, James Fraser1, Shan Yu1, Gayathri Balandaram1, Jeffrey M. Peters1, Pamela A. Hankey-Giblin1 1Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, 2Microscopy and Cytometry Facility, The Huck Institutes of Life Sciences, Pennsylvania State University JoVE 55445 Imunologia e Infecção
Isolering, karakterisering och rening av makrofager från vävnader som påverkas av fetma-relaterade Inflammation Joselyn N. Allen1, Adwitia Dey1, Ruth Nissly2, James Fraser1, Shan Yu1, Gayathri Balandaram1, Jeffrey M. Peters1, Pamela A. Hankey-Giblin1 1Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, 2Microscopy and Cytometry Facility, The Huck Institutes of Life Sciences, Pennsylvania State University JoVE 55445 Imunologia e Infecção