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Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
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JoVE Journal Chemistry
Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine

English

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2,720 Views

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11:04 min

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June 13, 2022

DOI:

10.3791/63705-v

DOI:
10.3791/63705-v

•

11:04 min
June 13, 2022

•

5 Views
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1Department of Chemistry,Hankuk University of Foreign Studies

Summary

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In this study, we prepare both enantiomers of aziridine-2-carboxylate, which are used in the asymmetric synthesis of alkaloids, including biemamide B and D, and (-)-epiallo-isomuscarine.

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Enantiopure AziridinesBiemamide BBiemamide DEpiallo-isomuscarineAsymmetric SynthesisCrystallizationLarge-scale PreparationNon-activated AziridinesAziridine-2 Carboxylate

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Cite this Article

Srivastava, N., Ha, H. Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine. J. Vis. Exp. (184), e63705, doi:10.3791/63705 (2022).

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